About Appendix
Appendix is an MCP server for agents handling health conversations. It searches medical literature and submits clinical encounters for review by a board-certified physician, who may provide a prescription when appropriate.
Key features
- 01Search medical literature and guidelines
- 02Submit encounters for physician review
- 03List conditions and medications
Use cases
- 01Find evidence for a health conversation
- 02Request physician review of a clinical letter
MCP support
The server exposes literature search, encounter submission, and condition and medication lookup tools to MCP clients. Physician guidance and prescriptions may follow clinical review when appropriate.
Configuration
Remote servers need no local install. Pick your client, then copy the config or install in one click.
https://mcp.appendix.com/mcpclaude mcp add --transport http appendixhealth https://mcp.appendix.com/mcp{"mcpServers":{"appendixhealth":{"type":"http","url":"https://mcp.appendix.com/mcp"}}}Open in Cursor{"servers":{"appendixhealth":{"type":"http","url":"https://mcp.appendix.com/mcp"}}}Open in VS Code{"mcpServers":{"appendixhealth":{"type":"http","url":"https://mcp.appendix.com/mcp"}}}{"mcpServers":{"appendixhealth":{"serverUrl":"https://mcp.appendix.com/mcp"}}}Run commands in a terminal; paste JSON into the client’s MCP config and restart. Servers that need sign-in will prompt on first connect.
Tools
3| Parameter | Type | Required | Description |
|---|---|---|---|
| query | string | Yes | Search query (clinical topic or question) |
| limit | integer | No | Max results to return (1-10, default 5) |
Details
From the project READMEAppendix MCP Server
Appendix turns any AI health conversation into a physician-reviewed opinion, with a prescription if you need one.
Your agent writes a medical encounter summary, submits it through our API, and a real doctor signs off.
Use the Appendix MCP server to search medical literature, submit clinical encounters, and receive clinical guidance and prescriptions from board-certified physicians. Learn more at appendix.com.
Installation
Claude Code
claude mcp add --transport http appendix https://mcp.appendix.com/mcp
Claude Desktop / Claude Web Connectors
Add to your Claude Desktop config (claude_desktop_config.json) or Claude.ai custom-connector form:
{
"mcpServers": {
"appendix": {
"url": "https://mcp.appendix.com/mcp"
}
}
}
Other clients
| Client | URL |
|---|---|
| Claude Code, Claude Desktop, Claude.ai connectors | https://mcp.appendix.com/mcp |
Anthropic Messages API (mcp_servers) | https://mcp.appendix.com/mcp |
The server speaks Streamable HTTP only — the current MCP spec transport (2025-03-26).
Available Tools
| Tool | Description |
|---|---|
search_knowledge_base | Search medical literature and treatment guidelines |
submit_encounter | Submit a clinical letter for physician review |
list_conditions | List available conditions and medications |
Development
npm install
npm run build
npm start
Watch mode:
npm run dev
Environment Variables
| Variable | Default | Description |
|---|---|---|
API_BASE_URL | https://api.appendix.com | Appendix API base URL |
PORT | 3001 | HTTP listener port |
Endpoints
| Method | Path | Purpose |
|---|---|---|
GET | /health | Health probe for the hosting platform |
POST GET DELETE | /mcp | Streamable HTTP transport (stateless mode) |
Comments
New to MCP?
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An open protocol that defines how AI applications connect to external tools and data in a uniform way. Clients talk to the model; MCP servers provide tools, resources and prompt templates. They exchange standard messages, so one server can be reused by many clients.